CME Journal of Medical Microbiology

A Preliminary in Vestigation into the Effects of a Soluble Dietary Fibre and Mineral Formulation on Post-Prandial Glucose Regulation and Satiation in Healthy Adults

Abstract

Michael Haynes

Prevalence of obesity and overweight has steadily increased over the past decade, urging the development, and refining of various methods of intervention to combat the epidemic. Glucomannan is a dietary fibre with gelling properties, contributing to satiety. Chromium picolinate is an artificial additive, initially suggested to be an essential trace element, contributing to lipid and carbohydrate metabolism. Fructo-oligosaccharides are among a group of calorie free prebiotics, contributing to mineral absorption. Here, we are presenting an open label, preliminary investigation, to explore the effect of a formulation containing glucomannan, chromium picolinate and fructo-oligosaccharides on post-prandial blood glucose modulation and hunger and satiation in 17 adults (Mean ± SD: age 26.35 ± 5.18 years; height 171 ± 11.22 cm; body weight 73.24 ± 13.23 kg; BMI 24.89 ± 2.72 kg/m2 ). Data have shown significant reductions in feelings of hunger (P = > .001), and desire to eat (P= > .001), with no significant effect on blood glucose control. These findings have suggested use of this formulation in dietary intervention, through controlling obesity related parameters.

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