Sisay Fisseha, Tigabu Addisu Lendado, Awoke Abraham and Desalegn Dawit Assele
Background Poor anti-diabetic medication adherence results in poor glycemic control and can induce treatment failures, accelerated complications, and increased risk of mortality. There is a lack of information on the level of adherence to anti-diabetic medication in the study area. Therefore, this study aimed to assess adherence and associated factors towards anti-diabetic medications among type II diabetic patients on follow-up at Wolaita Sodo University teaching referral hospital.
Methods A facility-based cross-sectional study was conducted among 418 type II diabetic patients. Morisky Medication Adherence Scale (MMAS) scores were used to measure the adherence level. Data were collected by a pretested intervieweradministered structured questionnaire. Data were coded and entered into EpiData version 3.2 and analyzed using STATA version 15. Binary logistic regression analysis was conducted to identify factors associated with adherence. An adjusted odds ratio, along with a 95% confidence interval, was reported to show the strength of the association. Variables with a p-value <0.05 were considered statistically significant. The goodness-of-fit was checked by the Hosmer–Lemeshow test.
Results The magnitude of antidiabetic adherence medication was found to be 68.9%. Age above 60 years [AOR: 3.24, CI:(1.44, 7.27)], college and above [AOR: 2.98, CI:(1.09, 8.11)], duration of diabetes [AOR: 2.58, CI:(1.47, 4.54)] and medication availability [AOR: 2.21, CI:(1.05, 4.64)] were positively associated with antidiabetic adherence medication, while diabetes complications [AOR: 0.147, CI:(0.081,0.265)] was negatively associated with antidiabetic adherence medication.
Conclusion The level of medication compliance was suboptimal in this study. Patients' ages, educational levels, diabetes complications, duration of diabetes, and access to medication in the hospital are independent factors associated with antidiabetic drug adherence. Strategies that further increase the availability of anti-diabetic drugs, provide counseling, and accentuate special attention for individuals who have developed diabetes complications may aid in boosting adherence leve