CME Journal of Clinical Case Reports

Analysis of Diaphragm Mobility in Patients With Chronic Obstructive Pulmonary Disease in Algeria

Abstract

Amine Meridj, Redouan Belala, Khaled Tlili and Yacine Djeghri

In addition to affecting the respiratory system, chronic obstructive pulmonary disease also decreases muscle mass. The respiratory muscles weaken, which impairs ventilation and exercise tolerance. According to recent studies, M-mode ultrasonography provides a dependable and user-friendly method for evaluating diaphragmatic mobility in patients with COPD.

Objective Evaluate diaphragmatic excursion by ultrasound in M-mode in patients with COPD and correlate with different clinical and ventilatory variables.

Methods We conducted a prospective, observational study from 2021 to 2024. A total of Sixty-one consecutive patients with spirometryconfirmed stable COPD were included after obtaining informed written consent. Demographic and clinical data, spirometric values, BMI, 6-minute walking test as well as blood gas and Measurement of and Excursion (EXdi) were collected for analysis. This is a prospective study conducted at Constantine Regional Military University Hospital

Results The mean diaphragmatic excursion, evaluated by ultrasound (EXdi), in our patients with COPD was 5.01 cm ± 1.48 cm, In our study a correlation between the EXdi and spirometric data (FVC; FEV1; FEV1/FVC) was objectified with (P < 0,001) the majority of our patients were classified grade 1 and grade 2 according to MMRC (Figur 4) the average of PaCO2 is 36,57 (mmHg), a negative correlation has been reported between L’EXdi and the dyspné MMRC (P < 0,001) The average BMI is 24.12 4.83 kg/m 2, with extreme values ranging from 14.6 to 36.9 kg/m 2, a positive correlation has been reported between L’EXdi and the BMI (P= 0,015) a positive rrelation has been reported between L’EXdi and the PaO2 (mmHg) (P =0,009),and a negative correlation has been reported between L’EXdi and the PaCO2 (mmHg) (P =0,022), The average distance travelled in this test was 470 129.37 m , our study has shown that the more EXdi increases, the distance patients travel increases (P =0,001)

Conclusion In patients with COPD, diaphragmatic mobility appears to be associated with airway obstruction and BMI,6- minute walking test as well as blood gas and perception of dyspnea

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