Mujahid Ali, Ali Akhtar, Waqas Akram, Mahtab Ahmad Khan, Muhammad Nadeem Alvi, Muhammad Abbas Raza, Israr Tanveer, Muhammad Hammad, Muhammad Sabtain Abbas, Hassan Ahmad and Mirza Usama
Objective: To determine factors related to the prevalence of drug compliance and insufficient adherence to lowering blood pressure treatment. Investigating patient-related factors and health systems associated with reduced compliance with blood pressure-lowering medications.
Method: This quantitative cross-section study was conducted in Johar Town, Lahore, from 17 to 31 March 2025 and is targeted at adult hypertensive patients. A sample of 350 18-year-old patients with hypertension diagnosed for more than 1 year took part in blood pressure-lowering medications and outpatient follow-up tests. Information was collected on health system factors and care driver factors for violations with patients with self-reported and revised scales to comply with Hill's bone.
Result: Of the 350 participants, 173 (49.4%) were males and 176 (50.6%) were females. Participants' income was categorized into 87 low-income class, 189 middle-income class, and 73 high-income class. The most frequent comorbidities included diabetes (72 patients) and heart failure (79 patients). Based on self-reports, 174 (49.7%) patients were unsuitable for blood pressurelowering medications. Patients who were affected by noncompliance included the number of drugs collected, side effects, and missed appointments. Patients who received three blood pressure-lowering medications were less likely to adhere compared to drug therapy (OR 0.8; 95% CI 0.3°C). The incidence of diarrhea as a side effect also reduced the lack of compliance (OR 0.9; 95% CI 0.5°C) and clinical appointments due to lack of change in compliance (OR 0.5; 95% CI 0.2°C). According to the modified Hill bone suitability scale, patients who could name the drug were quite glued (OR 1.4; 95% CI 0.8°2.5). Health system-related factors also played a role. Self-reports noted that lack of booking significantly reduced compliance (OR 0.4; 95% CI 0.2 4.7). A moderate correlation was found between self-reported compliance and modified Columbine scales.
Conclusion: The prevalence of compliance among hypertensive patients was 50.3%. Side effects of dizziness and cancellations due to unavailability of transport were factors related to non-attendance. Compliance with BP drugs and counseling on medication intake were both related to decreased noncompliance