International Journal of Clinical & Medical Surgery
ISSN: 3069-2067 | DOI: 10.64030/3069-2067
Dario Cattel, Francesca Steccanella, Giovanni Fabbrocile, Elio Donnarumma and Alessandro Puzziello
Granular cell tumor (GCTs) is a rare soft tissue neoplasm of neural origin, often challenging to diagnose at first presentation due to its resemblance to other lesions and pathologies. Axillary localization poses a particular diagnostic challenge because of its potential to mimic lymphoproliferative disorders or metastatic breast disease. Accurate identification is crucial to avoid inappropriate treatment.
Case presentation: We report the case of a 32-year-old Nigerian woman who presented with a painless, palpable mass in the left axilla, initially suspected to be an abnormal lymphadenopathy. Ultrasound and magnetic resonance imaging (MRI) revealed a well-circumscribed soft tissue lesion, making direct assessment essential for a definitive diagnosis. Complete surgical excision was performed. Final histopathological evaluation confirmed a benign granular cell tumor with negative surgical margins. The postoperative course was uneventful, and no recurrence was observed during follow-up.
Conclusions: This case highlights the importance of including granular cell tumor in the differential diagnosis of axillary masses. A multimodal diagnostic approach, incorporating imaging and histopathological confirmation, is essential for accurate diagnosis and appropriate treatment planning. Conventional open surgery remains a highly reliable and effective approach for achieving the best curative and prognostic outcome.