CME Journal of Clinical Case Reports
ISSN: 3067-7998 | DOI: 10.64030/3067-7998
Subrat Kumar Panigrahi, Smruti Ranjan Parida, Jitendra Das, Swati Pragyan Patro, Sital Agrawal, Raj Kumar Behera, Priyanka Mohanty and Nihar Ranjan Nayak
Introduction The mosquito Aedes lineatopennis belongs to the subgenus Neomelaniconion and functions as a transmission agent for both the West Nile virus and Rift Valley fever virus. It also responsible for spreading of Japanese encephalitis virus and canine heartworm. The medical significance of this species exists alongside a lack of available documentation about it. This study analyzed the genetic variation and evolutionary links by calculation of different indices within Aedes lineatopennis population for the first time. Further its vectorial capacity was examined through the analysis of the mitochondrial COI gene. The findings will provide important data regarding the species’ distribution throughout evolutionary development and ecological adaptations while uncovering possible public health concerns.
Results Our study detected 21 unique haplotypes alongside a haplotype diversity rate of 0.9754 and a variance reading of 0.00023. The COI gene sequences in Aedes lineatopennis displayed 256 segregating sites yet demonstrated low nucleotide diversity with a value of 0.10724. The analysis showed significant results for Harpending’s raggedness index (R2 = 0.0152) but the p-value exceeded 0.05. The D+ (1.88172) F+ (0.85790) and F (1.326) values from Fu and Li’s results were positive despite lacking statistical significance. The Tajima’s D statistic showed 1.53395 while Strobeck S registered at 0.487. The average evolutionary substitution rates at each site were estimated as 0.31, 0.60, 0.88, 1.22, and 1.99. Thymine/uracil formed 39.98% of the nucleotide composition while adenine followed at 29.53%, cytosine was 15.55%, and guanine made up 14.95%.
Conclusion The genetic diversity within the Aedes lineatopennis population reveals recent population expansion alongside possible selective pressures which could eventually lead to its establishment among other Aedes species. The species could become a higher risk to human health and present more challenges for its control. At this moment we must develop prevention strategies to stop its growth and establishment during initial developmental phases.