Journal of Gynecology and Reproductive Health

Predictors of Mortality in Adult ICU At Hakim Gizaw Referral Hospital from August 2022 to Augst 2024. Hospital-Based Retrospective Cohort Study in Resource Limited Setup

Abstract

Yidersal Demsie Denberu, Zemed Geleta Eshete, Enku Shiferaw Belayneh, Ermias Fikru Yesuf, Girma Deshimo Lema, Ananya Abate Shiferaw and Girma Gedeyon Seyoum

Background: Intensive Care Units (ICUs) are essential for managing critically ill patients. Despite advancements in medical care, ICU mortality rates remain high, particularly in low- and middle-income countries (LMICs). ICU outcomes are influenced by factors such as patient demographics, comorbidities, severity of illness, and interventions. This study investigates predictors of inpatient mortality in adult ICU patients at Hakim Gizaw Referral Hospital, Debre Berhan, Ethiopia.

Objectives: To determine ICU mortality and analyze the predictors of ICU mortality at Hakim Gizaw Referral Hospital from August 2022 to August 2024. Methods: A retrospective cohort study was conducted from August 2022 to August 2024, reviewing the medical records of 269 patients admitted to the ICU. Data were collected on demographics, admission diagnoses, vital signs, interventions, and complications. Statistical analyses, including bivariate and multivariate logistic regression, were used to identify predictors of ICU mortality.

Results: The ICU mortality rate was 30%. Advanced age (≥ 60 years), septic shock, organ failure, and mechanical ventilation were significant predictors of death, with septic shock and mechanical ventilation showing the highest risks. Other factors, such as comorbidities and vital signs, were not statistically significant but suggested trends of higher mortality in some subgroups.

Conclusion: This study highlights the critical factors influencing ICU mortality, with advanced age, septic shock, organ failure, and mechanical ventilation being the most significant predictors. These findings underscore the need for targeted interventions and improved resource allocation to enhance patient outcomes in ICUs.

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